Indianapolis Colts vs. Buffalo Bills Betting Odds, Analysis, NFL Pick

September 9, 2015   ·   OddsShark.com   ·   Jump to comments

The Buffalo Bills are 6-2 against the spread their last eight times out as underdogs, winning five of those contests outright. The Indianapolis Colts are 15-2 straight up and 12-3-2 ATS the last 17 times they've gone out as a favorite. So winning trends clash when the Bills and Colts, former longtime division rivals, renew acquaintances Sunday afternoon at Ralph Wilson Stadium.
 
Point spread: The Colts opened as 2.5-point favorites; the total was 48 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 23.8-20.9 Colts
 
Why the Colts can cover the spread
Indianapolis is coming off a third straight 11-5 season and an AFC Championship Game appearance. The Colts also went 10-5-1 ATS last year, so they're now 33-15 SU and 29-17-2 ATS with Andrew Luck as their starting quarterback.
Indy ranked third in the league in total offense, 22nd in rushing, 11th in to...

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