San Francisco 49ers vs. Carolina Panthers Betting Odds, Analysis, NFL Pick

September 16, 2016   ·   OddsShark.com   ·   Jump to comments

The Carolina Panthers covered 11 of 16 spreads last year on their way to the Super Bowl, but they came up empty in their season opener last week. Will Carolina fight a Super Bowl letdown this season? The Panthers will shoot for win No. 1 when they host the San Francisco 49ers on Sunday afternoon.
          
Point spread: The Panthers opened as 13.5-point favorites; the total was 48.5 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, per the Odds Shark computer: 25.4-16.0 Panthers (NFL picks on every game)
       
Why the 49ers can cover the spread
Expected to bring up the rear in the NFC West again this season, San Francisco opened the Chip Kelly era in style last week, shutting out the Los Angeles Rams 28-0 and winning outright as a three-point home underdog.
The 49ers took a 7-0 lead on their second possession of the game, scoring on...

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