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San Francisco 49ers vs. Arizona Cardinals Betting Odds, Analysis, NFL Pick

November 10, 2016   ·     ·   Jump to comments

The Arizona Cardinals (3-4-1) will look to end a two-game winless streak and stay in contention for an NFC playoff spot when they host the San Francisco 49ers (1-7) as double-digit home favorites. The Cardinals hope their recently completed bye week helped clear their minds and put them back on track as they face a San Francisco team that has lost seven straight games.
Point spread: The Cardinals opened as 12.5-point favorites; the total was 48 early in the week, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
NFL pick, via Odds Shark computer: 35.9-10.3 Cardinals (NFL picks on every game)
   
Why the 49ers can cover the spread
The 49ers have not been close in any of their last four games, losing all of them by double digits. But they are familiar with Arizona as an NFC West rival and hung tough in the first half of their last meeting back in Week 5 on a Thursday night. That game was tied 7-7 at halftime before the ...

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