Arizona Cardinals vs. San Francisco 49ers Betting Odds, Analysis, NFL Pick

December 24, 2014   ·   OddsShark.com   ·   Jump to comments

The San Francisco 49ers are 9-3 both straight up and against the spread in their last 12 meetings with the division-rival Arizona Cardinals, but this season it's the Cardinals who are battling for playoff seedings while the Niners are reduced to playing spoiler. Arizona, at 11-4, needs some help, but it can still claim the No. 1 overall seed in the NFC if it can get by the 7-8 Niners at Levi's Stadium Sunday.
 
Point spread: The 49ers opened as 3.5-point favorites; the total was 36.5 early in the week, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
 
NFL pick, via Odds Shark computer: 19.0-14.5 Cardinals
 
Why the Cardinals can cover the spread
The Cardinals laid an egg last week against the Seattle Seahawks, so they need a victory and losses by either the Seahawks or Green Bay Packers to snatch home-field advantage throughout the NFC playoffs. Arizona is playing with a third-string quarter...

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