Arizona Cardinals vs. San Francisco 49ers Betting Odds, Analysis, NFL Pick

November 25, 2015   ·   OddsShark.com   ·   Jump to comments

San Francisco owns the recent divisional rivalry with Arizona, winning 10 of the last 13 meetings, but the worm may be turning as the Cardinals have taken two of the last three meetings outright, and won all three against the spread. First place meets last place in the NFC West when Arizona takes on the 49ers at Levi's Stadium Sunday afternoon.
 
Point spread: Cardinals opened as 9.5-point favorites; the total was 44.5 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 28.9-18.4 Cardinals
 
Why the Cardinals can cover the spread
The Cardinals ride a four-game winning streak into this week's matchup after holding off Cincinnati last week 34-31. Arizona trailed the Bengals 14-7 at the half, rallied to take a 28-14 lead, allowed Cincy to tie the score at 31-31 late but kicked a field goal with two seconds left to seal the victory and the push as a three-point...

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