New England Patriots vs. Buffalo Bills Betting Odds, Analysis, NFL Pick

September 15, 2015   ·   OddsShark.com   ·   Jump to comments

The Buffalo Bills (1-0) have earned a lot of respect from oddsmakers following their impressive season-opening victory against the Indianapolis Colts and hope to make it two straight wins when they host the New England Patriots (1-0) on Sunday. This AFC East matchup is set as a close one on the odds despite the fact that the defending Super Bowl champion Patriots have won 26 of the past 29 meetings with the Bills.
 
Point spread: Patriots opened as 1.5-point favorites; the total was 46 early in the week, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
NFL pick, via Odds Shark computer: 24.2-21.8 Bills
 
Why the Patriots can cover the spread
New England has lost just once to Buffalo in a meaningful game since 2003, and that took place four years ago at Ralph Wilson Stadium in a 34-31 upset as a seven-point road favorite. Last year’s regular-season finale meant nothing to the Patriots, who obviously we...

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