San Francisco 49ers vs. Pittsburgh Steelers Betting Odds, Analysis, NFL Pick

September 17, 2015   ·   OddsShark.com   ·   Jump to comments

The San Francisco 49ers travel well, and the further from home they get the more profitable they've been. In fact, the Niners are 10-0 both straight up and against the spread in their last 10 regular-season games played in the Eastern Time Zone. San Francisco makes the first of four trips this season to the east when it visits Pittsburgh to take on the Steelers Sunday afternoon.
 
Point spread: The Steelers opened as 6.5-point favorites; the total was 45 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 25.9-23.0 Steelers
 
Why the 49ers can cover the spread
Reports of the Niners' demise may have been greatly exaggerated. San Francisco began the post-Harbaugh era Monday night with a 20-3 victory over Minnesota, winning outright as a two-point home dog.
The Niners outrushed the Vikings by a 230-71 margin, as Carlos Hyde—their new No. 1 ball-carr...

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